STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC16Tetratricopeptide repeat domain 16. (866 aa)    
Predicted Functional Partners:
TRIML2
Tripartite motif family like 2.
   
   0.809
YME1L1
YME1 like 1 ATPase.
    
 
 0.803
PERM1
PPARGC1 and ESRR induced regulator, muscle 1.
    
 
 0.802
MDH1B
Malate dehydrogenase 1B.
   
  
 0.799
STON2
Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.
      
 0.773
KLK4
Kallikrein related peptidase 4; Belongs to the peptidase S1 family.
    
 
 0.690
SLC25A33
Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.631
SLC25A36
Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.631
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.617
FOXN3-2
Forkhead box N3.
    
 
 0.593
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.