STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUBE1Tubulin epsilon 1; Belongs to the tubulin family. (513 aa)    
Predicted Functional Partners:
TUBD1
Tubulin delta chain; Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
   
 
0.705
SASS6
SAS-6 centriolar assembly protein.
   
  
 0.690
RHOT2
WD repeat domain 90.
   
 
 0.689
POC1B
POC1 centriolar protein B.
   
 
 0.632
PLK4
Polo like kinase 4.
   
 
 0.621
SEH1L
Centrosomal protein 192.
   
 
 0.599
NIN
Ninein.
   
 
 0.598
TUBG1
Tubulin gamma-1 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity).
   
 
0.598
DCLK1
Doublecortin like kinase 1.
    
 
 0.595
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.589
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.