STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LATS1Large tumor suppressor kinase 1. (1127 aa)    
Predicted Functional Partners:
MOB1B
MOB kinase activator 1B.
   
 0.995
MOB1A
MOB kinase activator 1A.
    
 0.994
YAP1
Yes associated protein 1.
   
 0.992
WWTR1
WW domain containing transcription regulator 1.
   
 0.983
SAV1
Salvador family WW domain containing protein 1.
    
 0.979
LIMD1
LIM domains containing 1.
    
 0.977
NF2
Neurofibromin 2.
    
 
 0.975
LATS2
Non-specific serine/threonine protein kinase.
  
 
0.962
STK3
Serine/threonine kinase 3.
   
0.960
AJUBA
Ajuba LIM protein.
    
 0.928
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.