STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VGLL4Vestigial like family member 4. (296 aa)    
Predicted Functional Partners:
TMEM167A
Protein kish; Involved in the early part of the secretory pathway.
      
 0.829
TEAD4
Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
   
 
 0.827
TEAD2
TEA domain transcription factor 2.
   
 
 0.810
IRF2BP2
Interferon regulatory factor 2 binding protein 2.
   
 
 0.785
VGLL3
Vestigial like family member 3.
      
 0.783
TEAD1
TEA domain transcription factor 1.
    
 
 0.775
TEAD3
TEA domain transcription factor 3.
    
 
 0.775
WASL
WASP like actin nucleation promoting factor.
   
  
 0.735
YAP1
Yes associated protein 1.
   
 
 0.693
WWTR1
WW domain containing transcription regulator 1.
   
 
 0.671
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.