STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF2BP3Insulin like growth factor 2 mRNA binding protein 3. (579 aa)    
Predicted Functional Partners:
RDH14
Uncharacterized protein.
    
 
 0.811
IGF2
Insulin like growth factor 2.
      
 0.716
H2BC1
Histone H2B; Belongs to the histone H2B family.
    
 
 0.680
YTHDF1
YTH N6-methyladenosine RNA binding protein 1.
   
 
 0.677
LIN28B
Lin-28 homolog B.
   
 
 0.663
AKR1E2
Aldo-keto reductase family 1 member E2.
   
  
 0.648
YTHDC1
YTH domain containing 1.
      
 0.636
SPECC1
Sperm antigen with calponin homology and coiled-coil domains 1.
      
 0.607
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
    
 
 0.584
EIF2A
Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
      
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.