STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REG3ARegenerating islet-derived 3 alpha. (176 aa)    
Predicted Functional Partners:
OXSM
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
      
 0.611
SPINK5
Serine peptidase inhibitor, Kazal type 5.
  
   
 0.579
SGMS2
Sphingomyelin synthase 2.
      
 0.563
PRDM5
Zinc finger protein.
    
 
 0.519
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1; Belongs to the glycosyltransferase 29 family.
      
 0.508
NGLY1
N-glycanase 1.
      
 0.499
DUOXA1
Dual oxidase maturation factor 1.
      
 0.491
USP53
Ubiquitin specific peptidase 53.
      
 0.487
DUOXA2
Dual oxidase maturation factor 2.
      
 0.475
CNDP1
Carnosine dipeptidase 1.
    
 
 0.473
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.