STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDIT4LDNA damage inducible transcript 4 like. (245 aa)    
Predicted Functional Partners:
AP3B2
AP-3 complex subunit beta.
      
 0.805
WFDC3
WAP four-disulfide core domain 3.
      
 0.789
DAPP1
Dual adaptor of phosphotyrosine and 3-phosphoinositides 1.
      
 0.787
LAMTOR3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
      
 0.782
EXTL1
Exostosin like glycosyltransferase 1; Belongs to the glycosyltransferase 47 family.
      
 0.769
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
      
 0.644
CCKBR
Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
      
 0.614
SCN3B
Sodium voltage-gated channel beta subunit 3.
      
 0.614
WFDC10B
WAP four-disulfide core domain 10B.
      
 0.575
WFDC13
WAP four-disulfide core domain 13.
      
 0.575
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.