STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (782 aa)    
Predicted Functional Partners:
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.
   
 
 0.966
RBM28
RNA binding motif protein 28.
   
 
 0.964
NIFK
Nucleolar protein interacting with the FHA domain of MKI67.
   
 
 0.964
CEP152
Centrosomal protein 152.
   
 
 0.938
PUM3
Pumilio RNA binding family member 3.
   
 
 0.927
RPF2
Ribosome production factor 2 homolog.
   
 
 0.927
UTP14A
Uncharacterized protein.
   
 
 0.918
RBM34
RNA binding motif protein 34.
   
 
 0.916
NOP2
NOP2 nucleolar protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.916
NSUN6
NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.912
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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