STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IER5Immediate early response 5. (312 aa)    
Predicted Functional Partners:
STX6
Syntaxin 6; Belongs to the syntaxin family.
      
 0.795
CDT1
Chromatin licensing and DNA replication factor 1.
      
 0.597
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3.
      
 0.560
COL6A3
Collagen type VI alpha 3 chain.
      
 0.482
VWA2
Von Willebrand factor A domain containing 2.
      
 0.482
STXBP5L
Syntaxin binding protein 5 like.
      
 0.478
RIPK4
Receptor interacting serine/threonine kinase 4.
    
 
 0.473
RHOV
Ras homolog family member V.
      
 0.465
EVC
EvC ciliary complex subunit 1.
      
 0.451
PPP2R2C
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
    
   0.448
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.