STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (229 aa)    
Predicted Functional Partners:
LOC100684659
ADAM_spacer1 domain-containing protein.
 
    
 0.856
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif 19.
 
    
 0.644
COMP
Cartilage oligomeric matrix protein.
   
 
 0.606
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9.
   
  
 0.591
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif 16.
 
 
 
 0.546
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7.
   
  
0.531
SIM1
SIM bHLH transcription factor 1.
   
  
 0.513
LENG8
Leukocyte receptor cluster member 8.
   
  
 0.501
RAB32
RAB32, member RAS oncogene family.
      
 0.483
SNRK
SNF related kinase.
   
 
 0.480
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.