STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB1Zinc finger/BTB domain-containing protein 1 isoform 1. (712 aa)    
Predicted Functional Partners:
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1.
      
 0.679
CCDC42
Coiled-coil domain containing 42.
    
 
 0.676
ARHGEF10
Rho guanine nucleotide exchange factor 10.
    
 
 0.621
ETNPPL
Ethanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
    
 
 0.619
HACD3
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
   
 
 0.614
BTBD1
BTB domain containing 1.
   
  
 0.606
ZNF608
Zinc finger protein 608.
   
  
 0.596
BRSK2
BR serine/threonine kinase 2.
      
 0.568
CNIH3
Cornichon family AMPA receptor auxiliary protein 3.
      
 0.522
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 
 0.520
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.