STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM126ATransmembrane protein 126A. (197 aa)    
Predicted Functional Partners:
TMUB1
Transmembrane and ubiquitin like domain containing 1.
      
 0.829
DHRS7
Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.827
TMEM41A
Transmembrane protein 41A.
      
 0.769
SEC11C
Signal peptidase complex catalytic subunit SEC11C; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
   
  
 0.765
OPA3
Outer mitochondrial membrane lipid metabolism regulator OPA3.
      
 0.724
NAV2
Neuron navigator 2.
      
 0.707
MARCHF5
Membrane associated ring-CH-type finger 5.
   
  
 0.690
RTN4IP1
Reticulon 4 interacting protein 1.
   
  
 0.690
FAM3C
Family with sequence similarity 3 member C.
      
 0.670
METTL7A
Methyltransferase like 7A.
   
  
 0.668
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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