STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LHX8LIM homeobox 8. (321 aa)    
Predicted Functional Partners:
FIGLA
Folliculogenesis specific bHLH transcription factor.
   
 
 0.740
SOX6
SRY-box 6.
    
 
 0.685
DLX1
Distal-less homeobox 1.
   
  
 0.654
TBC1D13
TBC1 domain family member 13.
 
 
    0.611
SST
Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin.
      
 0.591
LDB1
LIM domain binding 1.
    
 
 0.584
RIPK4
Receptor interacting serine/threonine kinase 4.
    
 
 0.581
SLC44A3
Solute carrier family 44 member 3; Belongs to the CTL (choline transporter-like) family.
   
  
 0.572
AJAP1
Adherens junctions associated protein 1.
   
  
 0.566
PPP1R3E
Protein phosphatase 1 regulatory subunit 3E.
      
 0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.