STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKDREJPolycystin family receptor for egg jelly. (2033 aa)    
Predicted Functional Partners:
ADAM20
ADAM metallopeptidase domain 20.
      
 0.780
ACRBP
Acrosin binding protein.
      
 0.738
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
   
 
0.731
KCNC4
Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family.
   
  
 0.700
PKD2L2
Polycystin 2 like 2, transient receptor potential cation channel.
   
 
0.695
ODF4
Outer dense fiber of sperm tails 4.
   
  
 0.680
ODF3
Outer dense fiber of sperm tails 3.
   
  
 0.678
PKD2
Polycystin 2, transient receptor potential cation channel.
    
 
0.663
ADAM2
ADAM metallopeptidase domain 2.
   
  
 0.643
CDPF1
Cysteine rich DPF motif domain containing 1.
 
    
 0.614
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.