STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMWDDM1 locus, WD repeat containing. (670 aa)    
Predicted Functional Partners:
SYMPK
Symplekin.
 
 
 
 0.808
WDR48
WD repeat domain 48.
   
 
 0.795
CTCFL
CCCTC-binding factor like.
    
 
 0.728
USP46
Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family.
   
 
 0.698
USP12
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.698
FBXO46
F-box protein 46.
   
  
 0.679
BHMG1
Basic helix-loop-helix and HMG-box containing 1.
      
 0.623
ZC3H6
Zinc finger CCCH-type containing 6.
    
 
 0.617
USP38
Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family.
   
 
 0.585
USP1
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.584
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.