STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX1Regulatory factor X1. (973 aa)    
Predicted Functional Partners:
RFXAP
Regulatory factor X associated protein.
    
 
 0.802
BCAP31
B cell receptor associated protein 31.
      
 0.739
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.737
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 
 0.723
KIAA0319
KIAA0319.
    
 
 0.684
IFT57
Intraflagellar transport 57.
      
 0.602
DCDC2
Doublecortin domain containing 2.
   
  
 0.592
CIITA
Class II major histocompatibility complex transactivator.
    
 
 0.588
POU6F1
POU domain protein.
   
 
 0.583
NFIC
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.544
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.