STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQP1Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. (373 aa)    
Predicted Functional Partners:
AQP9
Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.843
AQP11
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.796
RHAG
Ammonium transporter Rh type A; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. Involved in ammonia transport across the erythrocyte membrane. Seems to act in monovalent cation transport.
   
 
 0.747
AQP3
Uncharacterized protein.
  
 
0.729
AQP8
Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.664
SLC4A1
Anion exchange protein.
   
 
 0.651
F1PXE0_CANLF
Uncharacterized protein.
     
 0.628
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.616
GPD2
Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.599
AQP2
Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.589
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]