STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA4Pleckstrin homology domain containing A4. (778 aa)    
Predicted Functional Partners:
KLHL12
Adiponectin receptor 1.
   
 
 0.561
NME7
Nucleoside diphosphate kinase 7; Belongs to the NDK family.
    
 
 0.545
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
    
 
 0.535
GPBP1
GC-rich promoter binding protein 1.
      
 0.515
BPIFC
BPI fold containing family C.
      
 0.515
PDE1B
Phosphodiesterase.
    
 
 0.503
PLEKHA3
Pleckstrin homology domain containing A3.
      
 0.502
FICD
FIC domain containing.
   
  
 0.496
DBN1
Drebrin 1.
   
 
 0.432
LRTM1
Leucine rich repeats and transmembrane domains 1.
    
 
 0.422
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.