STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDXKPyridoxal kinase. (464 aa)    
Predicted Functional Partners:
PDXP
Pyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily.
    
 0.985
PNPO
Pyridoxamine 5'-phosphate oxidase.
    
 0.962
PLPBP
Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6.
  
  
 0.939
AOX4
Uncharacterized protein.
     
 0.925
AOX2
Uncharacterized protein.
     
 0.925
PHOSPHO2
Phosphatase, orphan 2.
     
 0.903
FDX2
2Fe-2S ferredoxin-type domain-containing protein.
   
 
 0.784
FDX1
Ferredoxin 1.
     
 0.782
BHMT
Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism.
      
 0.742
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
      
 0.704
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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