STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDKPTN_MK_C domain-containing protein. (143 aa)    
Predicted Functional Partners:
ALK
Tyrosine-protein kinase receptor.
    
 0.964
PTPRZ1
Protein tyrosine phosphatase receptor type Z1.
    
 0.839
HDGF
Heparin binding growth factor.
      
 0.707
PTN
Pleiotrophin.
    
0.694
STAT3
Signal transducer and activator of transcription.
     
 0.671
NCL
Nucleolin.
    
 
 0.623
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 0.617
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
      
 0.583
SORL1
Sortilin related receptor 1.
    
 
 0.578
JAK3
Tyrosine-protein kinase.
    
 0.563
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.