STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BOCBOC cell adhesion associated, oncogene regulated. (1121 aa)    
Predicted Functional Partners:
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.979
GAS1
Growth arrest specific 1.
    
 0.974
PTCH1
Patched 1.
    
 0.945
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.945
DHH
Desert hedgehog signaling molecule.
    
 0.934
PTCH2
Patched 2.
    
 0.933
CDON
Cell adhesion associated, oncogene regulated.
    
0.910
LRP2
LDL receptor related protein 2.
     
 0.901
SLITRK3
SLIT and NTRK like family member 3.
    
 
 0.783
BNIP2
BCL2 interacting protein 2.
    
 0.754
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.