STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (595 aa)    
Predicted Functional Partners:
PCGF5
Polycomb group ring finger 5.
   
  
 0.589
CLCN7
Chloride channel protein.
  
  
 0.540
ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family.
      
 0.532
DAB2IP
DAB2 interacting protein.
    
 
 0.519
WIPF2
WAS/WASL interacting protein family member 2.
   
  
 0.516
SLC9A3R1
Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
      
 0.515
SLC33A1
Solute carrier family 33 member 1.
      
 0.515
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
      
 0.515
ADNP
Activity dependent neuroprotector homeobox.
      
 0.514
ACOX3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
   
  
 0.511
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.