STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FASTKFas activated serine/threonine kinase. (712 aa)    
Predicted Functional Partners:
DNAJC25
DnaJ heat shock protein family (Hsp40) member C25.
      
 0.787
CTXN1
Cortexin 1.
      
 0.719
PFDN1
Uncharacterized protein.
      
 0.679
PDE6G
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones.
      
 0.671
MTNR1B
Melatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family.
      
 0.637
MCPH1
Microcephalin 1.
   
  
 0.578
MADCAM1
Mucosal vascular addressin cell adhesion molecule 1.
   
  
 0.567
SLC7A9
Solute carrier family 7 member 9.
   
  
 0.566
FXYD2
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
   
  
 0.563
GRSF1
G-rich RNA sequence binding factor 1.
   
 
 0.533
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.