STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA13Carbonic anhydrase 13; Belongs to the alpha-carbonic anhydrase family. (279 aa)    
Predicted Functional Partners:
CD1A8
Ig-like domain-containing protein.
   
  
 0.809
SLC4A2
Anion exchange protein.
   
 
 0.656
TOR3A
Torsin family 3 member A.
      
 0.618
SLC4A1
Anion exchange protein.
   
 
 0.608
RPF2
Ribosome production factor 2 homolog.
   
 
 0.599
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
   
  
 0.570
SLC4A5
Anion exchange protein.
   
 
 0.552
SLC4A8
Anion exchange protein.
   
 
 0.550
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
  
 
0.538
CA2
Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family.
  
  
0.533
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.