STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UGT2A3UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (546 aa)    
Predicted Functional Partners:
TM4SF4
Transmembrane 4 L six family member 4.
   
  
 0.693
SLC35A2
UDP-galactose translocator; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
      
 0.646
ADH4
Alcohol dehydrogenase 4 (class II), pi polypeptide.
   
  
 0.617
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
      
 0.540
CYP3A12
Cytochrome P450 3A12.
   
 0.511
SLC5A6
Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.507
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
     
 0.507
GLYAT
Glycine-N-acyltransferase.
   
  
 0.504
SLC2A5
Solute carrier family 2 member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.493
CYP3A4
Cytochrome P450 3A12; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
   
 0.483
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.