Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (445 aa)    
Predicted Functional Partners:
PAFAH1B3
Platelet activating factor acetylhydrolase 1b catalytic subunit 3.
    
 0.999
PAFAH1B2
Platelet activating factor acetylhydrolase 1b catalytic subunit 2.
   
 0.999
NDEL1
NudE neurodevelopment protein 1 like 1.
   
 0.993
DYNC1H1
Dynein cytoplasmic 1 heavy chain 1.
   
 0.992
DYNC1I2
Dynein cytoplasmic 1 intermediate chain 2.
   
 0.983
NUDC
Nuclear distribution C, dynein complex regulator.
   
 0.982
CLIP1
CAP-Gly domain containing linker protein 1.
   
 0.968
ENSCAFP00000059780
Uncharacterized protein.
    
 0.962
CKAP5
Cytoskeleton associated protein 5.
    
 0.956
PAFAH2
Platelet-activating factor acetylhydrolase.
     
 0.941
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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