MSI2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MSI2

Musashi RNA binding protein 2. (327 aa)

Predicted Functional Partners:

TRA2A

0.764

ZC3H14

0.735

QKI

0.653

SLK

0.561

CSTF2

0.542

TNPO2

0.535

CSTF2T

0.534

TNPO1

0.522

TNIK

0.496

PRSS48

0.492

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSTF2	CSTF2T	ENSCAFP00000025876	ENSCAFP00000042214	Cleavage stimulation factor subunit 2.	RRM domain-containing protein.	0.618
CSTF2	MSI2	ENSCAFP00000025876	ENSCAFP00000045367	Cleavage stimulation factor subunit 2.	Musashi RNA binding protein 2.	0.542
CSTF2T	CSTF2	ENSCAFP00000042214	ENSCAFP00000025876	RRM domain-containing protein.	Cleavage stimulation factor subunit 2.	0.618
CSTF2T	MSI2	ENSCAFP00000042214	ENSCAFP00000045367	RRM domain-containing protein.	Musashi RNA binding protein 2.	0.534
MSI2	CSTF2	ENSCAFP00000045367	ENSCAFP00000025876	Musashi RNA binding protein 2.	Cleavage stimulation factor subunit 2.	0.542
MSI2	CSTF2T	ENSCAFP00000045367	ENSCAFP00000042214	Musashi RNA binding protein 2.	RRM domain-containing protein.	0.534
MSI2	PRSS48	ENSCAFP00000045367	ENSCAFP00000011886	Musashi RNA binding protein 2.	Serine protease 48; Belongs to the peptidase S1 family.	0.492
MSI2	QKI	ENSCAFP00000045367	ENSCAFP00000030367	Musashi RNA binding protein 2.	Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).	0.653
MSI2	SLK	ENSCAFP00000045367	ENSCAFP00000015494	Musashi RNA binding protein 2.	STE20 like kinase.	0.561
MSI2	TNIK	ENSCAFP00000045367	ENSCAFP00000048600	Musashi RNA binding protein 2.	TRAF2 and NCK interacting kinase.	0.496
MSI2	TNPO1	ENSCAFP00000045367	ENSCAFP00000011990	Musashi RNA binding protein 2.	Transportin 1.	0.522
MSI2	TNPO2	ENSCAFP00000045367	ENSCAFP00000051986	Musashi RNA binding protein 2.	Transportin 2.	0.535
MSI2	TRA2A	ENSCAFP00000045367	ENSCAFP00000004119	Musashi RNA binding protein 2.	Transformer 2 alpha homolog.	0.764
MSI2	ZC3H14	ENSCAFP00000045367	ENSCAFP00000025680	Musashi RNA binding protein 2.	Zinc finger CCCH-type containing 14.	0.735
PRSS48	MSI2	ENSCAFP00000011886	ENSCAFP00000045367	Serine protease 48; Belongs to the peptidase S1 family.	Musashi RNA binding protein 2.	0.492
QKI	MSI2	ENSCAFP00000030367	ENSCAFP00000045367	Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).	Musashi RNA binding protein 2.	0.653
QKI	SLK	ENSCAFP00000030367	ENSCAFP00000015494	Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).	STE20 like kinase.	0.451
QKI	TRA2A	ENSCAFP00000030367	ENSCAFP00000004119	Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).	Transformer 2 alpha homolog.	0.673
SLK	MSI2	ENSCAFP00000015494	ENSCAFP00000045367	STE20 like kinase.	Musashi RNA binding protein 2.	0.561
SLK	QKI	ENSCAFP00000015494	ENSCAFP00000030367	STE20 like kinase.	Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).	0.451