Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRPEL2Prenylcysteine oxidase 1 like. (625 aa)    
Predicted Functional Partners:
AFAP1L1
Actin filament associated protein 1 like 1.
      
 0.841
VPS53
VPS53 subunit of GARP complex.
      
 0.816
GEMIN4
Gem nuclear organelle associated protein 4.
   
  
 0.811
RPH3AL
Rabphilin 3A like (without C2 domains).
      
 0.806
TDRD5
Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity); Belongs to the TDRD5 family.
   
  
 0.696
SYT10
Synaptotagmin 10.
      
 0.692
ZNF462
Zinc finger protein 462.
      
 0.692
CNTN6
Contactin 6.
      
 0.689
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
      
 0.610
ARRDC3
Arrestin domain containing 3.
      
 0.582
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.