DLA-DRA protein (Canis lupus familiaris) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

DLA-DRA

Ig-like domain-containing protein; Belongs to the MHC class II family. (342 aa)

Predicted Functional Partners:

HLA-DQB1

0.997

DLA-DMA

0.992

HLA-DQB2

0.987

CD74

0.987

CD4

0.984

F1PSQ5_CANLF

0.980

DLA-DOA

0.933

CD247

0.917

E2R820_CANLF

0.853

CAMP

0.828

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMP	CD4	ENSCAFP00000019004	ENSCAFP00000063394	Cathelicidin antimicrobial peptide.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.525
CAMP	DLA-DRA	ENSCAFP00000019004	ENSCAFP00000045482	Cathelicidin antimicrobial peptide.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.828
CAMP	F1PSQ5_CANLF	ENSCAFP00000019004	ENSCAFP00000001282	Cathelicidin antimicrobial peptide.	Uncharacterized protein.	0.726
CAMP	HLA-DQB1	ENSCAFP00000019004	ENSCAFP00000001171	Cathelicidin antimicrobial peptide.	Major histocompatibility complex, class II, DQ beta 2.	0.725
CAMP	HLA-DQB2	ENSCAFP00000019004	ENSCAFP00000001156	Cathelicidin antimicrobial peptide.	Major histocompatibility complex, class II, DQ beta 1.	0.583
CD247	CD4	ENSCAFP00000041707	ENSCAFP00000063394	Uncharacterized protein.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.717
CD247	DLA-DOA	ENSCAFP00000041707	ENSCAFP00000001280	Uncharacterized protein.	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.907
CD247	DLA-DRA	ENSCAFP00000041707	ENSCAFP00000045482	Uncharacterized protein.	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.917
CD247	E2R820_CANLF	ENSCAFP00000041707	ENSCAFP00000034736	Uncharacterized protein.	DUF1968 domain-containing protein.	0.540
CD247	F1PSQ5_CANLF	ENSCAFP00000041707	ENSCAFP00000001282	Uncharacterized protein.	Uncharacterized protein.	0.568
CD247	HLA-DQB1	ENSCAFP00000041707	ENSCAFP00000001171	Uncharacterized protein.	Major histocompatibility complex, class II, DQ beta 2.	0.910
CD247	HLA-DQB2	ENSCAFP00000041707	ENSCAFP00000001156	Uncharacterized protein.	Major histocompatibility complex, class II, DQ beta 1.	0.910
CD4	CAMP	ENSCAFP00000063394	ENSCAFP00000019004	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Cathelicidin antimicrobial peptide.	0.525
CD4	CD247	ENSCAFP00000063394	ENSCAFP00000041707	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Uncharacterized protein.	0.717
CD4	DLA-DOA	ENSCAFP00000063394	ENSCAFP00000001280	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	MHC class II antigen DO alpha; Belongs to the MHC class II family.	0.910
CD4	DLA-DRA	ENSCAFP00000063394	ENSCAFP00000045482	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Ig-like domain-containing protein; Belongs to the MHC class II family.	0.984
CD4	E2R820_CANLF	ENSCAFP00000063394	ENSCAFP00000034736	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	DUF1968 domain-containing protein.	0.599
CD4	F1PSQ5_CANLF	ENSCAFP00000063394	ENSCAFP00000001282	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Uncharacterized protein.	0.735
CD4	HLA-DQB1	ENSCAFP00000063394	ENSCAFP00000001171	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 2.	0.987
CD4	HLA-DQB2	ENSCAFP00000063394	ENSCAFP00000001156	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Major histocompatibility complex, class II, DQ beta 1.	0.971