node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ITGB1 | MCAM | ENSCAFP00000005722 | ENSCAFP00000045607 | Integrin beta; Belongs to the integrin beta chain family. | Melanoma cell adhesion molecule. | 0.532 |
ITGB1 | RAC1 | ENSCAFP00000005722 | ENSCAFP00000032062 | Integrin beta; Belongs to the integrin beta chain family. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.645 |
ITGB1 | RAC2 | ENSCAFP00000005722 | ENSCAFP00000002174 | Integrin beta; Belongs to the integrin beta chain family. | Rac family small GTPase 2. | 0.643 |
ITGB1 | RHOG | ENSCAFP00000005722 | ENSCAFP00000008817 | Integrin beta; Belongs to the integrin beta chain family. | Ras homolog family member G. | 0.579 |
KLHL35 | MCAM | ENSCAFP00000008050 | ENSCAFP00000045607 | Kelch like family member 35. | Melanoma cell adhesion molecule. | 0.540 |
MCAM | ITGB1 | ENSCAFP00000045607 | ENSCAFP00000005722 | Melanoma cell adhesion molecule. | Integrin beta; Belongs to the integrin beta chain family. | 0.532 |
MCAM | KLHL35 | ENSCAFP00000045607 | ENSCAFP00000008050 | Melanoma cell adhesion molecule. | Kelch like family member 35. | 0.540 |
MCAM | RAC1 | ENSCAFP00000045607 | ENSCAFP00000032062 | Melanoma cell adhesion molecule. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.515 |
MCAM | RAC2 | ENSCAFP00000045607 | ENSCAFP00000002174 | Melanoma cell adhesion molecule. | Rac family small GTPase 2. | 0.514 |
MCAM | RHOB | ENSCAFP00000045607 | ENSCAFP00000036770 | Melanoma cell adhesion molecule. | Ras homolog family member B. | 0.513 |
MCAM | RHOC | ENSCAFP00000045607 | ENSCAFP00000059310 | Melanoma cell adhesion molecule. | Uncharacterized protein. | 0.523 |
MCAM | RHOD | ENSCAFP00000045607 | ENSCAFP00000017411 | Melanoma cell adhesion molecule. | Ras homolog family member D. | 0.513 |
MCAM | RHOF | ENSCAFP00000045607 | ENSCAFP00000057366 | Melanoma cell adhesion molecule. | Ras homolog family member F, filopodia associated. | 0.513 |
MCAM | RHOG | ENSCAFP00000045607 | ENSCAFP00000008817 | Melanoma cell adhesion molecule. | Ras homolog family member G. | 0.514 |
MCAM | TJP2 | ENSCAFP00000045607 | ENSCAFP00000041484 | Melanoma cell adhesion molecule. | Tight junction protein ZO-2; Plays a role in tight junctions and adherens junctions; Belongs to the MAGUK family. | 0.500 |
RAC1 | ITGB1 | ENSCAFP00000032062 | ENSCAFP00000005722 | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | Integrin beta; Belongs to the integrin beta chain family. | 0.645 |
RAC1 | MCAM | ENSCAFP00000032062 | ENSCAFP00000045607 | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | Melanoma cell adhesion molecule. | 0.515 |
RAC1 | RAC2 | ENSCAFP00000032062 | ENSCAFP00000002174 | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | Rac family small GTPase 2. | 0.509 |
RAC1 | RHOB | ENSCAFP00000032062 | ENSCAFP00000036770 | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | Ras homolog family member B. | 0.623 |
RAC1 | RHOC | ENSCAFP00000032062 | ENSCAFP00000059310 | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | Uncharacterized protein. | 0.638 |