STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFIT3Interferon induced protein with tetratricopeptide repeats 3. (491 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 
 0.845
DDX58
DExD/H-box helicase 58.
   
 
 0.803
IFI44
Interferon induced protein 44.
   
  
 0.780
MX1
Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV).
   
  
 0.757
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
 
 0.747
OASL
2'-5' oligoadenylate synthetase-like 1.
   
 
 0.742
STAT1
Signal transducer and activator of transcription.
   
 
 0.741
USP18
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.726
IFI6
Interferon alpha inducible protein 6.
   
 
 0.677
ISG20
Interferon stimulated exonuclease gene 20.
   
  
 0.631
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.