STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF692Zinc finger protein 692. (563 aa)    
Predicted Functional Partners:
RNF166
Ring finger protein 166.
   
 
 0.796
CRBN
Cereblon.
    
 
 0.764
NAE1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 
 0.678
UBA3
Ubiquitin like modifier activating enzyme 3.
    
 
 0.636
TRIM41
Tripartite motif containing 41.
   
 
 0.577
RAB28-2
RAB28, member RAS oncogene family.
    
 
 0.572
RAB28
Uncharacterized protein.
    
 
 0.572
CENPA
Centromere protein A.
    
 
 0.550
LTB4R
Leukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.522
ESCO2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]