STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MFSD13AMajor facilitator superfamily domain containing 13A. (563 aa)    
Predicted Functional Partners:
WDR75
WD repeat domain 75.
      
 0.689
FAM110B
Family with sequence similarity 110 member B.
      
 0.680
NSMAF
Neutral sphingomyelinase activation associated factor.
      
 0.676
TRIM8
Tripartite motif containing 8.
      
 0.676
H2AZ2
Histone H2A; Belongs to the histone H2A family.
      
 0.672
TMEM68
Transmembrane protein 68.
      
 0.670
MFSD6L
Major facilitator superfamily domain containing 6 like.
      
 0.669
FBXL15
F-box/LRR-repeat protein 15; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2 (By similarity); Belongs to the FBXL15 family.
      
 0.659
UBXN2B
UBX domain protein 2B.
      
 0.653
CUEDC2
CUE domain containing 2.
      
 0.649
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.