STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP11Poly [ADP-ribose] polymerase. (400 aa)    
Predicted Functional Partners:
PARP8
Poly [ADP-ribose] polymerase.
   
  
 0.813
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.809
PARP2
Poly [ADP-ribose] polymerase.
    
 
 0.677
PKM
Multifunctional fusion protein; Belongs to the pyruvate kinase family.
   
  
 0.593
PARP4
Poly [ADP-ribose] polymerase.
   
 
 0.555
MACROD1
Mono-ADP ribosylhydrolase 1.
   
  
 0.536
MACROD2
Mono-ADP ribosylhydrolase 2.
   
  
 0.536
ETNK1
Ethanolamine kinase 1.
   
  
 0.532
RNF114
Ring finger protein 114.
   
 
 0.530
TRPT1
tRNA phosphotransferase 1.
  
  
 0.506
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.