STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (670 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 
 0.650
POLN
DNA polymerase nu.
      
 0.647
ZHX2
Zinc fingers and homeoboxes 2.
      
 0.587
TMEM107
Transmembrane protein 107.
   
  
 0.570
MMRN2
Multimerin 2.
   
 
 0.567
PSMA8
Proteasome subunit alpha type.
      
 0.560
ATP1B2
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
      
 0.560
TNFSF12
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
      
 0.560
ZBTB4
Zinc finger and BTB domain containing 4.
    
 
 0.559
CDC42
Cell division cycle 42.
    
 
 0.539
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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