STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COA4Cytochrome c oxidase assembly factor 4 homolog. (84 aa)    
Predicted Functional Partners:
SDHAF4
Succinate dehydrogenase complex assembly factor 4.
      
 0.716
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
    
 
 0.670
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
      
 0.577
LOC477556
GST C-terminal domain-containing protein.
      
 0.564
AP3S1
Adaptor related protein complex 3 subunit sigma 1.
      
 0.563
LYRM7
LYR motif containing 7; Belongs to the complex I LYR family.
      
 0.559
ENSCAFP00000054342
Uncharacterized protein; Belongs to the complex I LYR family.
      
 0.559
ENSCAFP00000063214
Uncharacterized protein; Belongs to the complex I LYR family.
      
 0.559
SCO1
SCO cytochrome c oxidase assembly protein 1.
   
  
 0.532
COA6
Cytochrome c oxidase assembly factor 6.
   
  
 0.522
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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