STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHDDSAlkyl transferase; Belongs to the UPP synthase family. (340 aa)    
Predicted Functional Partners:
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
   
 0.993
PDSS1
Decaprenyl diphosphate synthase subunit 1; Belongs to the FPP/GGPP synthase family.
  
 
 0.955
FDPS
Farnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.953
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
  
 
 0.952
PDSS2
Decaprenyl diphosphate synthase subunit 2; Belongs to the FPP/GGPP synthase family.
  
 
 0.952
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
   
 
 0.940
ENSCAFP00000060389
Nudix hydrolase domain-containing protein.
  
 
 0.865
COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
  
 
 0.858
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
   
 
 0.843
UBIAD1
UbiA prenyltransferase domain containing 1.
     
 0.821
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.