FOXP2 protein (Canis lupus familiaris) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

FOXP2

Forkhead box P2. (729 aa)

Predicted Functional Partners:

CNTNAP2

0.824

FOXP4

0.780

TBR1

0.748

NFATC2

0.748

CUX1

0.667

ASPM

0.652

SATB2

0.652

FOXP1

0.652

ISLR

0.650

TH

0.635

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPM	FOXP2	ENSCAFP00000016776	ENSCAFP00000047072	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	Forkhead box P2.	0.652
CNTNAP2	FOXP2	ENSCAFP00000005188	ENSCAFP00000047072	Contactin associated protein like 2.	Forkhead box P2.	0.824
CNTNAP2	SATB2	ENSCAFP00000005188	ENSCAFP00000036183	Contactin associated protein like 2.	DNA-binding protein SATB.	0.494
CUX1	FOXP1	ENSCAFP00000062672	ENSCAFP00000056417	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	Forkhead box P1.	0.401
CUX1	FOXP2	ENSCAFP00000062672	ENSCAFP00000047072	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	Forkhead box P2.	0.667
CUX1	SATB2	ENSCAFP00000062672	ENSCAFP00000036183	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	DNA-binding protein SATB.	0.891
CUX1	TBR1	ENSCAFP00000062672	ENSCAFP00000014694	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	T-box brain transcription factor 1.	0.808
FOXP1	CUX1	ENSCAFP00000056417	ENSCAFP00000062672	Forkhead box P1.	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	0.401
FOXP1	FOXP2	ENSCAFP00000056417	ENSCAFP00000047072	Forkhead box P1.	Forkhead box P2.	0.652
FOXP1	FOXP4	ENSCAFP00000056417	ENSCAFP00000002320	Forkhead box P1.	Forkhead box P4.	0.567
FOXP1	NFATC2	ENSCAFP00000056417	ENSCAFP00000017095	Forkhead box P1.	Nuclear factor of activated T cells 2.	0.544
FOXP1	SATB2	ENSCAFP00000056417	ENSCAFP00000036183	Forkhead box P1.	DNA-binding protein SATB.	0.485
FOXP1	TBR1	ENSCAFP00000056417	ENSCAFP00000014694	Forkhead box P1.	T-box brain transcription factor 1.	0.469
FOXP2	ASPM	ENSCAFP00000047072	ENSCAFP00000016776	Forkhead box P2.	Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).	0.652
FOXP2	CNTNAP2	ENSCAFP00000047072	ENSCAFP00000005188	Forkhead box P2.	Contactin associated protein like 2.	0.824
FOXP2	CUX1	ENSCAFP00000047072	ENSCAFP00000062672	Forkhead box P2.	Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).	0.667
FOXP2	FOXP1	ENSCAFP00000047072	ENSCAFP00000056417	Forkhead box P2.	Forkhead box P1.	0.652
FOXP2	FOXP4	ENSCAFP00000047072	ENSCAFP00000002320	Forkhead box P2.	Forkhead box P4.	0.780
FOXP2	ISLR	ENSCAFP00000047072	ENSCAFP00000026367	Forkhead box P2.	Immunoglobulin superfamily containing leucine rich repeat.	0.650
FOXP2	NFATC2	ENSCAFP00000047072	ENSCAFP00000017095	Forkhead box P2.	Nuclear factor of activated T cells 2.	0.748