STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000047301Uncharacterized protein. (88 aa)    
Predicted Functional Partners:
ANKRD27
Ankyrin repeat domain 27.
    
 
 0.975
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.945
SNX1
Sorting nexin 1.
   
 
 0.886
SNX2
Sorting nexin 2.
   
 
 0.883
TBC1D5
TBC1 domain family member 5.
    
 
 0.864
VPS26B
VPS26, retromer complex component B.
   
 
 0.860
VPS26A
VPS26, retromer complex component A.
   
 
 0.815
SNX4
Sorting nexin 4.
   
 
 0.806
CCP110
Centriolar coiled-coil protein 110.
    
 
 0.757
ITPA
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
  
  
 0.717
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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