PIGR protein (Canis lupus familiaris) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PIGR

Uncharacterized protein. (762 aa)

Predicted Functional Partners:

JCHAIN

0.998

PIGA

0.814

IL2

0.758

LTF

0.731

CSN3

0.613

SMAD6

0.605

LALBA

0.590

LOC484960

0.582

C3

0.581

LPO

0.578

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3	LTF	ENSCAFP00000027484	ENSCAFP00000020307	Complement C3.	Uncharacterized protein; Belongs to the transferrin family.	0.506
C3	PIGR	ENSCAFP00000027484	ENSCAFP00000047417	Complement C3.	Uncharacterized protein.	0.581
CSN3	LALBA	ENSCAFP00000004270	ENSCAFP00000013149	Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	0.947
CSN3	LPO	ENSCAFP00000004270	ENSCAFP00000025737	Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.	Lactoperoxidase.	0.563
CSN3	LTF	ENSCAFP00000004270	ENSCAFP00000020307	Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.	Uncharacterized protein; Belongs to the transferrin family.	0.700
CSN3	PIGR	ENSCAFP00000004270	ENSCAFP00000047417	Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.	Uncharacterized protein.	0.613
IL2	JCHAIN	ENSCAFP00000005941	ENSCAFP00000035905	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family.	Joining chain of multimeric IgA and IgM.	0.738
IL2	LTF	ENSCAFP00000005941	ENSCAFP00000020307	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family.	Uncharacterized protein; Belongs to the transferrin family.	0.483
IL2	PIGA	ENSCAFP00000005941	ENSCAFP00000059815	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family.	Ankyrin repeat and SOCS box containing 11.	0.431
IL2	PIGR	ENSCAFP00000005941	ENSCAFP00000047417	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family.	Uncharacterized protein.	0.758
JCHAIN	IL2	ENSCAFP00000035905	ENSCAFP00000005941	Joining chain of multimeric IgA and IgM.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family.	0.738
JCHAIN	LTF	ENSCAFP00000035905	ENSCAFP00000020307	Joining chain of multimeric IgA and IgM.	Uncharacterized protein; Belongs to the transferrin family.	0.515
JCHAIN	PIGA	ENSCAFP00000035905	ENSCAFP00000059815	Joining chain of multimeric IgA and IgM.	Ankyrin repeat and SOCS box containing 11.	0.861
JCHAIN	PIGR	ENSCAFP00000035905	ENSCAFP00000047417	Joining chain of multimeric IgA and IgM.	Uncharacterized protein.	0.998
LALBA	CSN3	ENSCAFP00000013149	ENSCAFP00000004270	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.	0.947
LALBA	LPO	ENSCAFP00000013149	ENSCAFP00000025737	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	Lactoperoxidase.	0.846
LALBA	LTF	ENSCAFP00000013149	ENSCAFP00000020307	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	Uncharacterized protein; Belongs to the transferrin family.	0.999
LALBA	PIGR	ENSCAFP00000013149	ENSCAFP00000047417	Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.	Uncharacterized protein.	0.590
LOC484960	LTF	ENSCAFP00000026509	ENSCAFP00000020307	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein; Belongs to the transferrin family.	0.413
LOC484960	PIGR	ENSCAFP00000026509	ENSCAFP00000047417	Anaphylatoxin-like domain-containing protein.	Uncharacterized protein.	0.582