STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRSProtein tyrosine phosphatase receptor type S. (1718 aa)    
Predicted Functional Partners:
LRRTM2
Leucine rich repeat transmembrane neuronal 2.
    
 
 0.804
TMPRSS9
Transmembrane serine protease 9; Belongs to the peptidase S1 family.
      
 0.801
DNM3
Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.715
NLGN4X
COesterase domain-containing protein.
    
 
 0.714
NTRK3
Tyrosine-protein kinase receptor.
   
 
 0.692
LRFN5
Leucine rich repeat and fibronectin type III domain containing 5.
   
 
 0.643
LRFN1
Leucine rich repeat and fibronectin type III domain containing 1.
   
 
 0.595
SLITRK1
SLIT and NTRK like family member 1.
    
 
 0.592
IL1RAP
Interleukin 1 receptor accessory protein.
    
 
 0.564
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
    
 
 0.549
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.