STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TUBTubby-like protein; Belongs to the TUB family. (645 aa)    
Predicted Functional Partners:
LOC100688800
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.644
SH2B1
SH2B adaptor protein 1.
      
 0.585
ANKS3
Ankyrin repeat and sterile alpha motif domain containing 3.
    
 
 0.580
STRADB
STE20 related adaptor beta.
      
 0.561
ARL13B
ADP ribosylation factor like GTPase 13B.
   
  
 0.530
TPI1
Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
      
 0.519
LOC610540
Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages; Belongs to the SFTPA family.
      
 0.515
IFT140
Uncharacterized protein.
    
 
 0.509
XXYLT1
Xyloside xylosyltransferase 1.
      
 0.497
HDAC6
Histone deacetylase 6.
    
 
 0.492
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.