STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000047935IF rod domain-containing protein; Belongs to the intermediate filament family. (415 aa)    
Predicted Functional Partners:
CASP7
Caspase 7; Belongs to the peptidase C14A family.
   
 0.836
TCAP
Titin-cap.
   
 
  0.808
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
 0.787
CASP6
Caspase 6; Belongs to the peptidase C14A family.
   
 0.778
COL1A1
Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).
   
 
 0.696
SNAI1
Snail family transcriptional repressor 1.
      
 0.680
ZEB1
Zinc finger E-box binding homeobox 1.
      
 0.676
DLA-DRA
Ig-like domain-containing protein; Belongs to the MHC class II family.
    
   0.660
SNAI2
Snail family transcriptional repressor 2.
      
 0.658
CD44
CD44 antigen.
   
  
 0.648
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.