STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CNP2',3'-cyclic nucleotide 3' phosphodiesterase. (453 aa)    
Predicted Functional Partners:
MAG
Myelin associated glycoprotein.
   
  
 0.886
MBP
Myelin basic protein.
   
  
 0.823
PLP1
Myelin proteolipid protein; This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
   
  
 0.788
OLIG2
Oligodendrocyte transcription factor 2.
      
 0.777
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.758
TTC25
Tetratricopeptide repeat domain 25.
 
 
   0.750
NDUFB7
NADH:ubiquinone oxidoreductase subunit B7.
   
   0.739
MOG
Myelin-oligodendrocyte glycoprotein; Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion. Belongs to the immunoglobulin superfamily. BTN/MOG family.
   
  
 0.736
NES
Nestin; Belongs to the intermediate filament family.
      
 0.674
OLIG1
Oligodendrocyte transcription factor 1.
      
 0.661
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.