STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAPK3-2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)    
Predicted Functional Partners:
PTPN7
Protein tyrosine phosphatase non-receptor type 7.
    
 
 0.708
RPS6KA1
Non-specific serine/threonine protein kinase.
   
 
0.661
STAT3
Signal transducer and activator of transcription.
    
 
 0.651
MAP2K3
Mitogen-activated protein kinase kinase 3.
  
 
0.616
MAPKAPK3
MAPK activated protein kinase 3; Belongs to the protein kinase superfamily.
  
 
0.615
DUSP6
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
    
 
 0.591
PEA15
Proliferation and apoptosis adaptor protein 15.
    
 
 0.589
FOXM1
Forkhead box M1.
    
 
 0.577
ELK1
ETS transcription factor ELK1.
    
 
 0.548
MBP
Myelin basic protein.
   
 
 0.541
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.