STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS2Protein inhibitor of activated STAT 2. (612 aa)    
Predicted Functional Partners:
ENSCAFP00000049214
Ubiquitin-like domain-containing protein.
    
 
 0.862
SUMO1
Rad60-SLD domain-containing protein.
    
 
 0.862
SUMO2
Small ubiquitin-related modifier.
    
 0.836
UBE2I
Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.802
STAT3
Signal transducer and activator of transcription.
   
 0.795
STAT1
Signal transducer and activator of transcription.
   
 0.776
STAT5A
Signal transducer and activator of transcription.
   
 0.755
STAT5B
Signal transducer and activator of transcription.
   
 0.755
STAT2
Signal transducer and activator of transcription.
   
 0.754
STAT4
Signal transducer and activator of transcription.
   
 0.754
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.