STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAFP00000048406Protein kinase domain-containing protein. (184 aa)    
Predicted Functional Partners:
S100B
Protein S100; Belongs to the S-100 family.
    
   0.970
MOB1A
MOB kinase activator 1A.
   
 
 0.792
CDC14B
Cell division cycle 14B.
   
 
 0.641
CDC14A
Cell division cycle 14A.
   
 
 0.641
FRYL
FRY like transcription coactivator.
    
 
 0.638
FRY
FRY microtubule binding protein.
    
 
 0.638
MOB2
MOB kinase activator 2.
    
 
 0.524
CDKN3
Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
   
 
 0.484
J9NVT8_CANLF
TYR_PHOSPHATASE_2 domain-containing protein.
   
 
 0.484
DIS3
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.
    
 
 0.482
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]