STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMTC2Transmembrane O-mannosyltransferase targeting cadherins 2. (857 aa)    
Predicted Functional Partners:
USP42
Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family.
   
  
 0.821
ERMP1
Endoplasmic reticulum metallopeptidase 1.
   
 
 0.814
MFSD6
Major facilitator superfamily domain containing 6.
      
 0.759
CSMD3
CUB and Sushi multiple domains 3.
   
 
 0.713
SEZ6L
Seizure related 6 homolog like.
   
 
 0.705
CPVL
Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family.
    
 
 0.703
DSTYK
Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
   
 
 0.696
GCSAML
Germinal center associated signaling and motility like.
      
 0.694
CHRND
Cholinergic receptor nicotinic delta subunit.
   
 
 0.692
OPCML
Opioid binding protein/cell adhesion molecule like.
   
 
 0.689
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.