HNF4A protein (Canis lupus familiaris) - STRING interaction network

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gene neighborhood

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Score

HNF4A

Hepatocyte nuclear factor 4 alpha. (484 aa)

Predicted Functional Partners:

AFM

0.792

PPARGC1A

0.726

HNF1A

0.607

NR0B2

0.600

MED1

0.599

TAT

0.594

PCK1

0.573

NCOR2

0.564

NCOA1

0.563

NCOR1

0.558

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFM	HNF4A	ENSCAFP00000066373	ENSCAFP00000048717	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.	Hepatocyte nuclear factor 4 alpha.	0.792
AFM	TAT	ENSCAFP00000066373	ENSCAFP00000032798	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.739
HNF1A	HNF4A	ENSCAFP00000015433	ENSCAFP00000048717	HNF1 homeobox A.	Hepatocyte nuclear factor 4 alpha.	0.607
HNF1A	MED1	ENSCAFP00000015433	ENSCAFP00000024203	HNF1 homeobox A.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.653
HNF4A	AFM	ENSCAFP00000048717	ENSCAFP00000066373	Hepatocyte nuclear factor 4 alpha.	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.	0.792
HNF4A	HNF1A	ENSCAFP00000048717	ENSCAFP00000015433	Hepatocyte nuclear factor 4 alpha.	HNF1 homeobox A.	0.607
HNF4A	MED1	ENSCAFP00000048717	ENSCAFP00000024203	Hepatocyte nuclear factor 4 alpha.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.599
HNF4A	NCOA1	ENSCAFP00000048717	ENSCAFP00000006049	Hepatocyte nuclear factor 4 alpha.	Nuclear receptor coactivator.	0.563
HNF4A	NCOR1	ENSCAFP00000048717	ENSCAFP00000053648	Hepatocyte nuclear factor 4 alpha.	Nuclear receptor corepressor 1.	0.558
HNF4A	NCOR2	ENSCAFP00000048717	ENSCAFP00000010374	Hepatocyte nuclear factor 4 alpha.	Nuclear receptor corepressor 2.	0.564
HNF4A	NR0B2	ENSCAFP00000048717	ENSCAFP00000018058	Hepatocyte nuclear factor 4 alpha.	Nuclear receptor subfamily 0 group B member 2.	0.600
HNF4A	PCK1	ENSCAFP00000048717	ENSCAFP00000046431	Hepatocyte nuclear factor 4 alpha.	Phosphoenolpyruvate carboxykinase 1.	0.573
HNF4A	PPARGC1A	ENSCAFP00000048717	ENSCAFP00000050517	Hepatocyte nuclear factor 4 alpha.	PPARG coactivator 1 alpha.	0.726
HNF4A	TAT	ENSCAFP00000048717	ENSCAFP00000032798	Hepatocyte nuclear factor 4 alpha.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.594
MED1	HNF1A	ENSCAFP00000024203	ENSCAFP00000015433	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	HNF1 homeobox A.	0.653
MED1	HNF4A	ENSCAFP00000024203	ENSCAFP00000048717	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Hepatocyte nuclear factor 4 alpha.	0.599
MED1	NCOA1	ENSCAFP00000024203	ENSCAFP00000006049	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor coactivator.	0.762
MED1	NCOR1	ENSCAFP00000024203	ENSCAFP00000053648	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 1.	0.601
MED1	NCOR2	ENSCAFP00000024203	ENSCAFP00000010374	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor corepressor 2.	0.729
MED1	NR0B2	ENSCAFP00000024203	ENSCAFP00000018058	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Nuclear receptor subfamily 0 group B member 2.	0.624