node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BYSL | DSTYK | ENSCAFP00000002354 | ENSCAFP00000014726 | Bystin like. | Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. | 0.848 |
BYSL | ENSCAFP00000050780 | ENSCAFP00000002354 | ENSCAFP00000050780 | Bystin like. | Ubiquitin-like domain-containing protein. | 0.770 |
BYSL | MED20 | ENSCAFP00000002354 | ENSCAFP00000002348 | Bystin like. | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.799 |
BYSL | RPS27A | ENSCAFP00000002354 | ENSCAFP00000031429 | Bystin like. | Ubiquitin-like domain-containing protein. | 0.770 |
BYSL | USP49 | ENSCAFP00000002354 | ENSCAFP00000048728 | Bystin like. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.960 |
DSTYK | BYSL | ENSCAFP00000014726 | ENSCAFP00000002354 | Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. | Bystin like. | 0.848 |
DSTYK | MED20 | ENSCAFP00000014726 | ENSCAFP00000002348 | Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.794 |
DSTYK | USP49 | ENSCAFP00000014726 | ENSCAFP00000048728 | Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.769 |
ENSCAFP00000050780 | BYSL | ENSCAFP00000050780 | ENSCAFP00000002354 | Ubiquitin-like domain-containing protein. | Bystin like. | 0.770 |
ENSCAFP00000050780 | RPS27A | ENSCAFP00000050780 | ENSCAFP00000031429 | Ubiquitin-like domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.405 |
ENSCAFP00000050780 | TAF10 | ENSCAFP00000050780 | ENSCAFP00000009728 | Ubiquitin-like domain-containing protein. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.710 |
ENSCAFP00000050780 | TRRAP | ENSCAFP00000050780 | ENSCAFP00000045167 | Ubiquitin-like domain-containing protein. | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. | 0.654 |
ENSCAFP00000050780 | UBA52 | ENSCAFP00000050780 | ENSCAFP00000021714 | Ubiquitin-like domain-containing protein. | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] | 0.972 |
ENSCAFP00000050780 | USP49 | ENSCAFP00000050780 | ENSCAFP00000048728 | Ubiquitin-like domain-containing protein. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.730 |
MED20 | BYSL | ENSCAFP00000002348 | ENSCAFP00000002354 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Bystin like. | 0.799 |
MED20 | DSTYK | ENSCAFP00000002348 | ENSCAFP00000014726 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. | 0.794 |
MED20 | TAF10 | ENSCAFP00000002348 | ENSCAFP00000009728 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. | 0.529 |
MED20 | USP49 | ENSCAFP00000002348 | ENSCAFP00000048728 | Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.719 |
RPS27A | BYSL | ENSCAFP00000031429 | ENSCAFP00000002354 | Ubiquitin-like domain-containing protein. | Bystin like. | 0.770 |
RPS27A | ENSCAFP00000050780 | ENSCAFP00000031429 | ENSCAFP00000050780 | Ubiquitin-like domain-containing protein. | Ubiquitin-like domain-containing protein. | 0.405 |